1262967-24-7 Usage
Uses
Used in Organic Synthesis:
4-Biphenylboronic acid MIDA ester is used as a protected boronic acid in organic synthesis for its ability to participate in selective and iterative cross-coupling sequences without unwanted reactions. This feature is particularly valuable in complex molecule assembly and the construction of diverse chemical libraries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Biphenylboronic acid MIDA ester is utilized as a key intermediate in the synthesis of various biologically active compounds, including drug candidates. Its stability and reactivity under specific coupling conditions facilitate the development of new drugs with improved pharmacological properties.
Used in Material Science:
4-Biphenylboronic acid MIDA ester is employed in material science as a building block for the creation of novel materials with tailored properties. Its compatibility with cross-coupling reactions allows for the synthesis of functional materials for applications in electronics, optoelectronics, and nanotechnology.
Used in Research and Development:
In research and development settings, 4-Biphenylboronic acid MIDA ester serves as a valuable tool for exploring new reaction pathways and understanding the fundamental aspects of cross-coupling chemistry. Its stability and reactivity make it an ideal candidate for studying the mechanisms of boronic acid derivatives in various coupling reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1262967-24-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,9,6 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1262967-24:
(9*1)+(8*2)+(7*6)+(6*2)+(5*9)+(4*6)+(3*7)+(2*2)+(1*4)=177
177 % 10 = 7
So 1262967-24-7 is a valid CAS Registry Number.
1262967-24-7Relevant articles and documents
One-Pot Homologation of Boronic Acids: A Platform for Diversity-Oriented Synthesis
Muir, Calum W.,Vantourout, Julien C.,Isidro-Llobet, Albert,Macdonald, Simon J. F.,Watson, Allan J. B.
, p. 6030 - 6033 (2015)
Formal homologation of sp2-hybridized boronic acids is achieved via cross-coupling of boronic acids with conjunctive haloaryl BMIDA components in the presence of a suitably balanced basic phase. The utility of this approach to provide a platform for diversity-oriented synthesis in discovery medicinal chemistry is demonstrated in the context of the synthesis of a series of analogues of a BET bromodomain inhibitor.
