1263191-69-0

Upstream product

• 138998-47-7 ethyl α<(N,N-dimethylamino)methylene>-2,3,4,5-tetrafluoro-β-oxobenzenepropanoate 
• 94695-48-4 2,3,4,5-tetrafluorobenzoyl chloride 
• 1201-31-6 2,3,4,5-tetrafluorobenzoic acid 
• 1239015-74-7 ethyl 1-(1-ethoxy-1-oxo-3-phenylpropan-2-yl)-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 

Downstream Products

• 1263191-64-5 1-(1-carboxy-2-phenylethyl)-6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 

Relevant academic research and scientific papers

Microwave-assisted synthesis and bioactivities of novel quinoline lactones

A facile, high efficiency microwave-assisted method was established for synthesizing novel quinoline lactones. All the synthesized compounds were characterized by 1H NMR, infrared spectrum, mass spectrum and elementary analysis. The preliminary bioassays

The simple synthesis and antimicrobial activity of novel fluoroquinolone derivatives from natural amino acid salts

A simple synthetic route was developed to prepare novel fluoroquinolone derivatives from amino acid salts. A facile route preparing the quinolone intermediates in one pot was explored which can facilitate the industrial operation. A series of new compounds were prepared conveniently and characterized by IR, 1H NMR, MS, and elemental analysis. The preliminary bioassays results revealed that they have certain antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Aspergillus fumigatus. Springer Science+Business Media, LLC 2010.