126330-90-3 Usage
Chemical Properties
White solid
Uses
(R)-2-Piperazinecarboxylic acid dihydrochloride can be used as a starting material for the synthesis of (R)-enantiomers of anthramycin analogs, which are potential antiproliferative agents. It can also be employed in the preparation of piperazinemethanol chiral ligands, which can be utilized in the enantioselective borane reduction of aromatic ketones, ketimine, and oxime ether.
Check Digit Verification of cas no
The CAS Registry Mumber 126330-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,3,3 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 126330-90:
(8*1)+(7*2)+(6*6)+(5*3)+(4*3)+(3*0)+(2*9)+(1*0)=103
103 % 10 = 3
So 126330-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H/t4-;;/m1../s1
126330-90-3Relevant articles and documents
SYNTHESIS AND CONVERSIONS OF PIPERAZINE-2-CARBOXYLIC ACID
Kutina, N. N.,Zhikhareva, G. P.,Anisimova, O. S.,Yakhontov, L. N.
, p. 693 - 696 (2007/10/02)
A method has been developed for the synthesis of methyl piperazinium-2-carboxylate dihydrochloride (overall yield 46percent) and piperazinium-2-carboxylic acid dihydrochloride (overall yield 36percent), from ethylene diamine through N,N'-di(trifluoroacetyl)ethylenediamine and methyl N,N'-di(trifluoroacetyl)piperazine-2-carboxylate.The N,N'-dinitroso derivatives were synthesized.