126334-84-7

Basic information

• Product Name: ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE
• Synonyms: Ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate ,97%;2-ChloroMethyl-4-phenyl-quinoline-3-carboxylicacidethylester;-4-phenylquinoline-3-carboxylate hydrochloride;Ethyl 2-(chloromethyl)
• CAS NO: 126334-84-7
• Molecular Formula: C₁₉H₁₆ClNO₂
• Molecular Weight: 325.8
• Mol File: 126334-84-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 469.2 °C at 760 mmHg
• Flash Point: 237.5 °C
• Appearance: /
• Density: 1.233 g/cm³
• Vapor Pressure: 5.63E-09mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE(126334-84-7)
• EPA Substance Registry System: ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE(126334-84-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 126334-84-7(Hazardous Substances Data)

Usage

Chemical Properties

Yellow solid

InChI:InChI=1/C19H16ClNO2/c1-2-23-19(22)18-16(12-20)21-15-11-7-6-10-14(15)17(18)13-8-4-3-5-9-13/h3-11H,2,12H2,1H3

Upstream product

• 638-07-3 ethyl (2-chloroaceto)acetate 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Downstream Products

• 144528-33-6 2,3-dihydro-2-(2-methylbenzyl)-9-phenyl-1H-pyrrolo<3,4-b>quinolin-1-one 
• 144549-69-9 2,3-dihydro-2-(4-fluorobenzyl)-9-phenyl-1H-pyrrolo<3,4-b>quinolin-1-one 
• 144528-35-8 2-(2-chlorobenzyl)-2,3-dihydro-9-phenyl-1H-pyrrolo<3,4-b>quinolin-1-one 

Relevant articles and documents

One-pot synthesis of novel 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates

A facile and efficient synthesis of novel ethyl 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates and the corresponding acids through the one-pot three-step reaction of ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate with a series of salicylalde

Synthesis and antibacterial activity of substituted quinoline derivatives

An efficient and convenient method is reported for the synthesis of various substituted quinolines through the condensation of o-amino aryl carbonyls with ketones containing an active methylene group in the presence of CuSO4·5H2O as

An efficient access to the synthesis of novel 12-phenylbenzo[6,7]oxepino[3, 4-b]quinolin- 13(6H)-one derivatives

An efficient access to the tetracyclic-fused quinoline systems, 12-phenylbenzo[6,7]oxepino[3,4-b]quinolin-13(6H)-one derivatives 4a-l, is described, involving the intramolecular Friedel-Crafts acylation reaction of 2-(phenoxymethyl)-4-phenylquinoline-3- c