1263368-91-7

Upstream product

• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 41939-98-4 C₉H₁₁N₃O₂ 
• 1122-71-0 2-(Hydroxymethyl)-6-methylpyridine 

Downstream Products

• 1263369-16-9 C₄₄H₆₄N₆O₇ 
• 1263369-14-7 Br^(1-)*C₂₈H₃₃N₆O⁽¹⁺⁾ 
• 1263369-15-8 C₂₆H₃₄N₆O 

Relevant academic research and scientific papers

Effect of substituent in pyridine-2-carbaldehydes on their heterocyclization to 1,2,4-triazines and 1,2,4-triazine 4-oxides

A series of substituted pyridine-2-carbaldehydes were brought into heterocyclization with isonitrosoacetophenone hydrazones, followed by aromatization by the action of oxidants or by dehydration in boiling acetic acid. As a result, substituted 3-(pyridin-2-yl)-1,2,4-triazines or 3-(pyridin-2-yl)-1,2,4-triazine 4-oxides were formed. 6-Formylpyridine-2-carbonitrile failed to undergo heterocyclization, 6-methylpyridine-2-carbaldehyde and methyl 6-formylpyridine-3-carboxylate can be converted to both 1,2,4-triazine and 1,2,4-triazine 4-oxide derivative, and only 1,2,4-triazine 4 oxides were obtained from 6-bromopyridine-2-carbaldehyde and 6-formyl-3-phenylpyridine-2-carbonitrile. Convenient procedures were proposed for the synthesis of some initial pyridinecarbaldehydes.

1,2,4-Triazine method of bipyridine ligand synthesis for the preparation of new luminescent Eu(III) complexes

The 'triazine' methodology for the synthesis of functionalized bipyridine ligands proved to be a convenient method for the preparation of luminescent Eu(III) complexes. The approach allows flexible construction of chromophore and coordination sphere with control of photophysical properties. Europium(III) complexes [Eu1]-[Eu5] prepared in this way exhibit intense long-life metal-centered luminescence in aqueous media. The aromatic substituent in the position 5 of bipyridine has a significant influence on luminescence parameters and is used to introduce functionality for bioconjugation. The complexes [Eu4] and [Eu5] bearing primary amine groups are ready-to-go luminescent 'tags' for peptide labeling.