1263375-27-4

Upstream product

• 1263371-46-5 (1S,3R)-3-(5'-chloro-6-(3-fluorobenzylamino)-2,4'-bipyridin-2'-yl-amino)cyclopentanol 
• 1263374-08-8 5'-chloro-2'-fluoro-N-(3-fluorobenzyl)-[2,4'-dipyridine]-6-amine 
• 1263374-07-7 6-bromo-N-(3-fluorobenzyl)pyridine-2-amine 
• 626-05-1 2,6-Dibromopyridine 
• 100-82-3 (3-fluorophenyl)methanamine 

Downstream Products

• 1263375-28-5 N₂'-((1R,3R)-3-azidocyclopentyl)-5'-chloro-N₆-(3-fluorobenzyl)-2,4'-bipyridine-2',6-diamine 
• 1263371-54-5 N₂'-((1R,3R)-3-aminocyclopentyl)-5'-chloro-N₆-(3-fluorobenzyl)-2,4'-bipyridine-2',6-diamine 

Relevant academic research and scientific papers

PYRIMIDINE BIARYL AMINE COMPOUNDS AND THEIR USES

The present invention provides a pyrimidine compound of formula (I): wherein one of X and Y but not both is N, and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tantomers, diastereomers, deuterated versions, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds