126338-44-1

Upstream product

• 126338-58-7 2-methyl-4-diphenylphosphinyl-1-butene 
• 113619-54-8 4-Diphenylphosphanyl-2-methyl-butan-1-ol 
• 1079-66-9 chloro-diphenylphosphine 
• 4124-07-6 homoallyldiphenylphosphane 
• 54067-17-3 diphenylmethylphosphine-borane complex 
• 714956-55-5 (3-methyl-3-butenyl)diphenylphosphine-borane complex 
• 714956-58-8 1,1-dihydrido-2,2-diphenyl-5-methyl-1,2-boraphosphinane 

Downstream Products

• 136492-51-8 (1R,3R)-3-((E)-2-Chloro-3,3,3-trifluoro-propenyl)-2,2-dimethyl-cyclopropanecarboxylic acid 4-(diphenyl-phosphinoyl)-2-methyl-butyl ester 

Relevant academic research and scientific papers

Mechanistic variations in ionic hydrogenation of unsaturated phosphine and amine boranes

Internal hydride transfer occurs when tethered carbocations are generated from unsaturated phosphine or phosphinite boranes. 3-Methylenecyclohexyl-derived boranes 12 or 18 react with MsOH to give ionic hydrogenation products with high syn-selectivity. With unsaturated amine boranes, initial hydrogen evolution gives BH2(OMs) complexes, but IH occurs using excess MsOH in a slower second stage. A diastereoselective reaction occurs from 26b using camphorsulfonic acid (first stage) and MsOH (second stage), affording 33 (68% ee) after hydrolysis.

Intramolecular hydroboration of unsaturated phosphine boranes

Homoallylic phosphine boranes undergo intramolecular hydroboration upon activation by triflic acid. The reaction occurs via an intermediate B- trifluorosulfonyloxyborane complex such as 15, followed by SN1-like or SN2-like displaceme

The Stereochemistry of Organometallic Compounds. XXXVII. Regio- and Stereo-control in the Rhodium-Catalysed Hydroformylation of Some Alkenylphosphines

Good to excellent regiocontrol can be obtained for the internal product of rhodium-catalysed hydroformylation of a range of alkenylphosphines.Excellent stereo- as well as regio-control can also be obtained for reactions of some cyclic alkenylphosphines.

EXTENSION OF THE HORNER-WITTIG REACTION TO THE SYNTHESIS OF E-ALKENES WITH CHIRAL SUBSTITUENTS: STEREOCHEMICAL CONTROL BY ACYL TRANSFER

Single crystalline diastereoisomers of hydroxyalkyl phosphine oxides (and hence functionalised E-alkenes) can be isolated, even when other chiral centres are present in the molecule, if they are made by acyl transfer.