1263407-24-4

Basic information

• Product Name: (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid
• Synonyms: (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid
• CAS NO: 1263407-24-4
• Molecular Weight: 359.229
• Mol File: 1263407-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid(1263407-24-4)
• EPA Substance Registry System: (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid(1263407-24-4)

Safety Data

• Hazardous Substances Data: 1263407-24-4(Hazardous Substances Data)

Upstream product

• 601525-80-8 (5-trityl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid 
• 109904-25-8 N-trityl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine 
• 28783-41-7 6,7-dihydro-4H-thieno[3,2-c]pyridine hydrochloride 
• 204205-33-4 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone 
• 1263407-33-5 C₇H₁₀BNO₂S*C₇H₈O₃S 

Downstream Products

• 150322-43-3 prasugel 

Relevant articles and documents

An improvement to the preparation of prasugrel hydrochloride

An efficient synthesis of prasugrel, a thienopyridine ADP-receptor antagonists, is described. A thienopyridine intermediate was prepared by N-protection, boric acid substitution and N-substitution. After acid hydrolysis of the methyl ether and subsequent acetylation, prasugrel was obtained with a total yield of 50% after seven linear steps from 4,5,6,7-tetrahydrothieno [3,2-c]pyridine and 2-bromo-1-cyclopropyl-2-(2- fluorophenyl)ethan-1-one as raw materials.