1263469-87-9

Upstream product

• 53603-94-4 stigmasterol methyl ether 
• 391871-69-5 (S)-2-(benzyloxy)-3-methylbutanoic acid 
• 51231-23-3 3α,5-cyclo-22-hydroxy-5α-23,24-bisnorcholan-6β-ol 6-methyl ether 
• 129919-92-2 (S)-2-(benzyloxy)-3-methylbutane-1-ol 
• 53139-42-7 stigmasteryl tosylate 
• 83-48-7 Stigmasterol 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 
• 1263469-81-3 2-(((S)-2-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)propyl)sulfonyl)benzo[d]thiazole 
• 110840-39-6 (S)-(+)-2-(benzyloxy)-3-methylbutanal 
• 1263469-79-9 2-(((S)-2-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethylhexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)propyl)thio)benzo[d]thiazole 

Relevant academic research and scientific papers

Access to functionalized steroid side chains via modified Julia olefination

Various functionalized steroidal side chains were conveniently accessed by a modified Julia olefination strategy using a common sulfone donor and an appropriate α-branched aldehyde acceptor. For the coupling of these hindered classes of reaction partners (and in contrast to typically observed trends), the benzothiazolyl(BT)-sulfone anion gave superior outcomes compared to the phenyltetrazolyl(PT)-sulfone anion.