1263474-57-2

Upstream product

• 1232892-80-6 5-methyl-3-(4-methyl-3-nitro-phenyl)-1H-pyrazole 
• 86864-60-0 2-(tert-butyldimethylsilyloxy)ethyl bromide 
• 76358-45-7 tert-butyldimethylsilyl chloride 
• 5333-27-7 1-(4-methyl-3-nitro-phenyl)-ethanone 

Relevant academic research and scientific papers

FUSED TRIAZOLE AMINES AS P2X7 MODULATORS

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein X, Y, R1, R2, and R3 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of dise

DIHYDROPYRIMIDONE AMIDES AS P2X7 MODULATORS

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5, Ra and Rb are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.

DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, R1, R2, R3, R4, R5 and R6 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.