126349-57-3

Upstream product

• 62-53-3 aniline 
• 13574-13-5 Boc-Glu(OBzl)-OH 
• 1186060-38-7 Boc-L-Glu(OBn)-SH 
• 1330059-20-5 N-α-tert-butoxycarbonyl-γ-benzyl ester L-glutamine 9-fluorenylmethyl thioester 
• 1676-73-9 L-glutamic acid γ-benzyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 117997-81-6 5-(benzyloxy)-2-(tert-butoxycarbonylamino)-5-oxopentanoic acid 

Downstream Products

• 947274-33-1 tert-butyl (2-oxo-1-phenylpiperidin-3-yl)carbamate 
• 99405-61-5 tert-butyl 2-(phenylcarbamoyl)pyrrolidine-1-carboxylate 
• 947274-34-2 C₂HF₃O₂*C₁₁H₁₄N₂O 
• 1259528-85-2 C₂HF₃O₂*C₁₁H₁₄N₂O 
• 1259528-80-7 N-phenyl-1-(phenylsulfonyl)pyrrolidine-2-carboxamide 
• 1259528-82-9 N-(2-(3-carbamoyl-4-hydroxyphenyl)-2-oxoethyl)-N-phenyl-1-(phenylsulfonyl)pyrrolidine-2-carboxamide 
• 1259528-83-0 tert-butyl-5-hydroxy-1-oxo-(phenylamino)pentan-2S-ylcarbamate 
• 5626-54-0 5-oxopyrrolidine-2-carboxanilide 
• 1259536-25-8 N-(2-oxo-1-phenylpiperidin-3-yl)benzenesulfonamide 
• 1259536-37-2 N-benzyl-N-(2-oxo-1-phenylpiperidin-3-yl)-benzenesulfonamide 
• 1259536-39-4 benzyl 4-(tert-butoxycarbonylamino)-5-oxo-5-(N-(2-oxo-1-phenylpiperidin-3-yl)phenylsuIfonamido)pentanoate 

Relevant academic research and scientific papers

Controlled ring-opening polymerization of α-amino acid N-carboxy-anhydride by frustrated amine/borane Lewis pairs

In this communication, we presented a novel strategy to control the ROP of α-amino acid N-carboxy-anhydrides using the concept of frustrated Lewis pairs (FLPs). An FLP intermediate containing an interaction between the bulky borane Lewis acid and the amine groups of the propagation chain end is essential to accomplish the polypeptide synthesis with well-defined structures under mild conditions.

Processes for forming amide bonds and compositions related thereto

The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.

N-PHENYL-1-SULFONYL-2-PYRROLIDINE CARBOXAMIDE LIBRARIES FOR DRUG DISCOVERY

New compounds are continually being sought for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenyl-pyrrolidine 2-carboxamides which can be used in the search for, and identification of, new lead compounds that could m

N-(1-PHENYL-2-OXO-3-PIPERIDYL SULPHONAMIDE LIBRARIES FOR DRUG DISCOVERY

Novel compounds are continually sought after to treat and prevent disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for contributing to the search and identification of new lead compounds which can modulate the functi

N-PHENYL-1-SULFONYL-2-PYRROLIDINE CARBOXAMIDES LIBRARIES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which can be biologically and pharmacologically traced, in order to be used in the search fo

LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides which can be biologically and pharmacologically traced, in order to be used in the search for, and identification of, new lead compounds that can modulate the functional activity of a biological target.

N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for being biologically and pharmacologically screened, and to contribute to the explorat

LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which can be biologically and pharmacologically traced, in order to be used in the search fo

N-(1-PHENYL-2-OXO-3-PIPERIDYL)SULPHONAMIDE LIBRARIES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides which can be biologically and pharmacologically traced, in order to be used in the search for,

LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR DRUG DISCOVERY

Novel compounds are continually sought after to treat and prevent disorders. The invention relates to N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides useful for contributing to the search and identification of new lead compounds which can modulate the functi