5626-54-0Relevant academic research and scientific papers
Controlled ring-opening polymerization of α-amino acid N-carboxy-anhydride by frustrated amine/borane Lewis pairs
Zhang, Hongyuan,Nie, Yanzhao,Zhi, Xinmei,Du, Haifeng,Yang, Jing
supporting information, p. 5155 - 5158 (2017/07/12)
In this communication, we presented a novel strategy to control the ROP of α-amino acid N-carboxy-anhydrides using the concept of frustrated Lewis pairs (FLPs). An FLP intermediate containing an interaction between the bulky borane Lewis acid and the amine groups of the propagation chain end is essential to accomplish the polypeptide synthesis with well-defined structures under mild conditions.
Studies on pyrrolidinones. Synthesis and reactivity of some N-protected pyroglutamic derivatives
Rigo,Erb,El Ghammarti,Gautret,Couturier
, p. 1599 - 1604 (2007/10/03)
The synthesis of pyroglutamoyl chloride N-protected by a methoxycarbonyl or a trifluoroacetyl group is described. Some aspects of the reactivity of these compounds and intermediates have been studied.
