1263499-10-0Relevant articles and documents
Organocatalytic enantioselective strecker synthesis of α-quaternary α-trifluoromethyl amino acids
Enders, Dieter,Gottfried, Katharina,Raabe, Gerhard
supporting information; experimental part, p. 3147 - 3152 (2011/02/22)
The first organocatalytic enantioselective Strecker synthesis of α-quaternary α-trifluoromethylated amino acids has been developed. Employing Takemoto's thiourea catalyst the nucleophilic addition of trimethylsilyl cyanide to trifluoromethyl ketimines aff