1263508-05-9Relevant academic research and scientific papers
2-Aroylindoles from o-bromochalcones via Cu(i)-catalyzed SNAr with an azide and intramolecular nitrene C-H insertion
Goriya, Yogesh,Ramana, Chepuri V.
, p. 7790 - 7792 (2014/07/08)
A simple procedure for the synthesis of 2-aroylindole derivatives comprising a one-pot CuI-catalyzed SNAr reaction of o-bromochalcones with sodium azide and subsequent intramolecular cyclization through nitrene C-H insertion has been developed. This protocol is also applicable with the 2′-bromocinnamates giving the indole-2-carboxylates. This journal is the Partner Organisations 2014.
Domino approach to 2-aroyltrimethoxyindoles as novel heterocyclic combretastatin A4 analogues
Arthuis, Martin,Pontikis, Renée,Chabot, Guy G.,Quentin, Lionel,Scherman, Daniel,Florent, Jean-Claude
experimental part, p. 95 - 100 (2011/02/25)
Two series of 2-aroyltrimethoxyindoles were designed to investigate the effects of the replacement of the trimethoxyphenyl ring of phenstatin with a trimethoxyindole moiety. These compounds were efficiently prepared through a domino palladium-catalyzed se
