1263786-41-9Relevant academic research and scientific papers
Diastereo-and enantioselective synthesis of oxazine and oxazolidine derivatives with a chiral quaternary carbon center under multifunctional catalysis
Jin, Zhichao,Wang, Xiao,Huang, Huicai,Liang, Xinmiao,Ye, Jinxing
supporting information; scheme or table, p. 564 - 567 (2011/04/25)
An easy one-pot, multistep cascade reaction which could afford a series of substituted benzo[d]pyrido[2,1-b]oxazolidine and [1,3]oxazine derivatives in a highly enantio-(up to 98% ee) and diastereoselective (4:1 to >20:1 dr) manner with generally good to excellent yields (up to 99%) has been developed. This well designed strategy could be applied to a wide scope of substrates under mild conditions with simple operations.
