1263865-01-5

Basic information

• Product Name: N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
• Synonyms: N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
• CAS NO: 1263865-01-5
• Molecular Weight: 446.939
• Mol File: 1263865-01-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine(1263865-01-5)
• EPA Substance Registry System: N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine(1263865-01-5)

Safety Data

• Hazardous Substances Data: 1263865-01-5(Hazardous Substances Data)

Upstream product

• 1263868-24-1 2,4-dichloro-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine 
• 312312-85-9 7-phenyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4-(3H,5H)-dione 
• 312312-82-6 7-Phenyl-6,7-dihydrocyclopenta[e][1,3]oxazine-2,4(3H,5H)-dione 
• 312312-81-5 2-Amino-7-phenyl-6,7-dihydrocyclopenta[e][1,3]oxazin-4(5H)-one 
• 312312-75-7 ethyl 3-phenyl-2-oxocyclopentane-1-carboxylate 
• 1235491-93-6 4-(4-chloro-1H-imidazol-1-yl)-3-methoxybenzenamine 
• 1263868-25-2 2-chloro-N-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 
• 1235491-92-5 4-chloro-1-(2-methoxy-4-nitrophenyl)-1H-imidazole 
• 825-54-7 cyclopent-1-en-1-ylbenzene 
• 1198-34-1 2-Phenylcyclopentanone 
• 1009-36-5 2-chloro-5-nitroanisole 
• 100-58-3 phenylmagnesium bromide 
• 120-92-3 cyclopentanone 

Downstream Products

• 1263865-03-7 (R)-N₂-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N₄-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine 
• 1263865-02-6 (S)-N²-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-N⁴-methyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine 

Relevant articles and documents

Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481

A triazine hit identified from a screen of the BMS compound collection was optimized for potency, in vivo activity, and off-target profile to produce the bicyclic pyrimidine γ-secretase modulator BMS-932481. The compound showed robust reductions of Aβsub