126401-45-4Relevant academic research and scientific papers
PEPTIDES HAVING RENIN INHIBITORY ACTIVITY, THEIR PREPARATION AND USE
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, (2008/06/13)
Compounds of formula (I): STR1 [in which: R 1 is heterocyclic group having 5 or 6 ring atoms, or--NR 7 R 8, where R 7 is alkyl and R 8 is optionally substituted phenyl, optionally substituted phenylalkyl or cycloalkyl; R 2 is optionally substituted phenyl
Asymmetric synthesis of 2-substituted-3-aminocarbonyl propionic acid.
Nishi,Sakurai,Sato,Kataoka,Morisawa
, p. 2200 - 2203 (2007/10/02)
An asymmetric synthetic route to 2-substituted-3-aminocarbonyl propionic acid, which is the significant component of low-molecular-weight renin inhibitors, is described. The key step of this synthesis is diastereoselective alkylation by using chiral oxazo
