126415-80-3Relevant academic research and scientific papers
Reactivity of Dimethyl N-(Ethoxycarbonylmethyl)iminodithiocarbonate with Carbonyl Compounds in Basic Medium
Alvarez-Ibarra, Carlos,Lopez-Ranz, Maria M.,Lopez-Sanchez, Maria I.,Orellana, Guillermo,Ortiz, Paloma,Quiroga, Maria L.
, p. 1577 - 1584 (2007/10/02)
The reactivity of dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate with aromatic aldehydes and reactive ketones has been studied.Ethyl 3-aryl-2-(methylcarbonylamino)acrylates (1) are obtained with aromatic aldehydes by ring-opening isomerization of the intermediate 5-aryl-4-ethoxycarbonyl-2-methylthio-4,5-dihydro-1,3-oxazoles (2).With ketones it has been shown that the cycloalkanones give rise to the corresponding alkylidene derivatives by a reaction path identical with that of aromatic aldehydes, whereas hexafluoropropanone and 1,1,1-trifluoropropanone display duality in acting as both acylating reagents and carbonyl compounds.
