126416-05-5Relevant academic research and scientific papers
Selective nitroaldol condensations over heterogeneous catalysts in the presence of supercritical carbon dioxide
Ballini, Roberto,Noe, Marco,Perosa, Alvise,Selva, Maurizio
supporting information; experimental part, p. 8520 - 8528 (2009/04/05)
(Chemical Equation Presented) At 40-60°C, in the presence of heterogeneous catalysts based on Al2O3, supercritical carbon dioxide not only acts as a good solvent for the reaction of aromatic and aliphatic aldehydes with 1-nitroalkanes but, most importantly, it also allows the selectivity to be tuned between the competitive formation of β-nitroalcohols and nitroalkenes (from the Henry reaction and the nitroaldol condensation, respectively). In particular, when the pressure (and the density) of the supercritical phase is enhanced from 80 to 140 bar, the nitroalkene's selectivity increases, on average, from ～60 to >90%. Experiments show that, in the same pressure range, a steep increase of the concentration profiles of reactant aldehydes takes place. By contrast, under solvent-free conditions, the reaction usually proceeds with a higher conversion, but nitroalkanols are the major products.
Oxidative cleavage of nitroalkenes with hydrogen peroxide in environmentally acceptable solvents
Bortolini, Olga,De Nino, Antonio,Fogagnolo, Marco,Fantin, Giancarlo,Mariuolo, Loredana,Tocci, Amedeo
, p. 472 - 473 (2008/02/02)
Hydrogen peroxide serves as an efficient oxidant for the nitroalkene C=C bond cleavage to aldehydes in ionic liquids. Copyright
PREPARATION OF ACYCLIC NITRO OLEFINS FROM β-TRIMETHYLSILOXY NITRO COMPOUNDS
Lee, Kilsung,Oh, Dong Young
, p. 3055 - 3060 (2007/10/02)
An efficient process for the preparation of acyclic nitro olefins is described, which consisted of improved nitro aldol reaction to give β-trialkylsiloxy nitro compounds and the direct or indirect elimination of water.
