1264175-87-2

Upstream product

• 1264175-79-2 (2R,3S,E)-N,2,8-trimethoxy-N,4-dimethyl-3-((triethylsilyl)oxy)oct-4-enamide 
• 1264175-80-5 (4R,5S,E)-4,10-dimethoxy-6-methyl-5-((triethylsilyl)oxy)dec-6-en-3-one 
• 330150-89-5 (S)-4-((tert-butyldiphenylsilyl)oxy)-3-methoxybutanal 
• 1264175-73-6 (E)-ethyl 6-methoxy-2-methylhex-2-enoate 
• 1264175-74-7 (E)-6-methoxy-2-methylhex-2-en-1-ol 
• 1264175-75-8 (E)-6-methoxy-2-methylhex-2-enal 
• 1264175-76-9 (4R,5S)-3-((2R,3S,E)-3-hydroxy-2,8-dimethoxy-4-methyloct-4-enoyl)-4-methyl-5-phenyloxazolidin-2-one 
• 1264175-78-1 (4R,5S)-3-((2R,3S,E)-2,8-dimethoxy-4-methyl-3-((triethylsilyl)oxy)oct-4-enoyl)-4-methyl-5-phenyloxazolidin-2-one 
• 21071-24-9 4-methoxybutanal 
• 29006-01-7 Methyl 4-methoxybutyrate 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 124655-05-6 (S)-methyl 4-(tert-butyldiphenylsilyloxy)-3-hydroxybutanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1264175-88-3 (2S,4S,5R,7R,8S,E)-1-((tert-butyldiphenylsilyl)oxy)-4,8-dihydroxy-2,7,13-trimethoxy-5,9-dimethyltridec-9-en-6-one 
• 1264175-89-4 C₃₄H₅₂O₆⁽¹⁸⁾OSi 
• 1264175-90-7 C₃₄H₅₂O₇⁽¹⁸⁾OSi 

Relevant academic research and scientific papers

18O assisted analysis of a γ,δ-epoxyketone cyclization: Synthesis of the C16-C28 fragment of ammocidin D

The C16-C28 fragment common to the cytotoxic macrolide ammocidin D has been prepared by a stereospecific 5-exo closure of a γ,δ-epoxyketone followed by a rearrangement to a pyran acetal. The reaction pathway was traced by 18O labeling of the ke