126424-79-1

Basic information

• Product Name: 3H-Pyrrolizin-3-one,hexahydro-,(R)-(9CI)
• Synonyms: 3H-Pyrrolizin-3-one,hexahydro-,(R)-(9CI)
• CAS NO: 126424-79-1
• Molecular Formula: C7H11NO
• Molecular Weight: 125.17
• Product Categories: PYRROLIDINE
• Mol File: 126424-79-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3H-Pyrrolizin-3-one,hexahydro-,(R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrrolizin-3-one,hexahydro-,(R)-(9CI)(126424-79-1)
• EPA Substance Registry System: 3H-Pyrrolizin-3-one,hexahydro-,(R)-(9CI)(126424-79-1)

Safety Data

• Hazardous Substances Data: 126424-79-1(Hazardous Substances Data)

Upstream product

• 87184-80-3 5-tert-butyldimethylsilyloxypentanal 
• 188415-33-0 (R)-2-(2,2,2-Tris-ethoxycarbonyl-ethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 188415-34-1 2-Ethoxycarbonyl-2-(R)-1-pyrrolidin-2-ylmethyl-malonic acid diethyl ester 
• 59378-81-3 1-(tert-butoxycarbonyl)prolin-2R-ol 
• 68832-13-3 D-prolinol 
• 126424-76-8 pyrrolam A 

Downstream Products

• 643-20-9 pyrrolizidine 
• 126424-76-8 pyrrolam A 

Relevant articles and documents

Synthesis of indolizidine, pyrrolizidine and quinolizidine ring systems by proline-catalyzed sequential α-amination and HWE olefination of an aldehyde

A general procedure for the synthesis of azabicyclic ring systems viz. indolizidine, pyrrolizidine and quinolizidine has been developed utilizing proline-catalyzed sequential α-amination and Horner-Wadsworth-Emmons (HWE) olefination of an aldehyde as the key step. This method can be further extended to the synthesis of various biologically active natural products containing azabicyclic ring systems.

Metabolic Products of Microorganism, 256. Pyrrolams, New Pyrrolizidinones Produced by Streptomyces olivaceus

Pyrrolams A to D (1-4), biosynthetically new pyrrolizidinones produced by Streptomyces olivaceus, have been discovered by chemical screening.Their structures have been determined by spectroscopic methods and by a comparison of (R)-dihydropyrrolam A (5) with a synthetic sample obtained from (S)-proline.The pyrrolams differ from the necine bases found in plant-originating pyrrolizidine alkaloids by their less complicated structures.