1264243-25-5

Upstream product

• 132286-79-4 N-α-(t-butoxycarbonyl)-L-glutamic γ-allyl ester 
• 1264239-42-0 C₁₅H₁₉NO₄*ClH 
• 1264239-47-5 C₂₁H₂₂N₂O₈S 
• 1264239-51-1 C₂₂H₂₄N₂O₈S 
• 1264239-56-6 (S)-5-allyl 1-benzyl 2-(methylamino)pentanedioate hydrochloride 
• 100-39-0 benzyl bromide 
• 4869-59-4 3-mercapto benzoic acid 
• 90887-44-8 3-(acetylthio)benzoic acid 
• 1264243-63-1 3-(acetylthio)benzoyl chloride 
• 1264240-87-0 C₂₅H₂₇NO₆S 
• 1264240-92-7 (S)-5-allyl 1-benzyl 2-(3-mercapto-N-methylbenzamido)pentanedioate 
• 1264241-01-1 allyl N-2-[(2S,4R)-4-[(tert-butoxycarbonyl)-amino]-2-(hydroxymethyl)tetrahydro-1H-pyrrol-1-yl]-2-oxoethyl-N-methylcarbamate 
• 1264243-44-8 tert-butyl (3R,5S)-5-(hydroxymethyl)pyrrolidin-3-ylcarbamate hydrochloride 
• 1264243-21-1 C₄₀H₅₂N₄O₁₀S 

Downstream Products

• 1264223-88-2 benzyl (4S,6R,15S)-6-[(tert-butoxycarbonyl)amino]-11,16-dimethyl-9,12,17-trioxo-2-thia-8,11,16-triazatricyclo[16.3.1.0^4,8]docosa-1⁽²²⁾,18,20-triene-15-carboxylate 
• 1264223-94-0 benzyl (4S,6R,15S)-6-[(tert-butoxycarbonyl)amino]-11,16-dimethyl-2,2,9,12,17-pentaoxo-2λ⁶-thia-8,11,16-triazatricyclo[16.3.1.0^4,8]docosa-1(22),18,20-triene-15-carboxylate 

Relevant academic research and scientific papers

CONFORMATION-LOCKED, SYNTHETIC MACROCYCLIC COMPOUND

PROBLEM TO BE SOLVED: To provide a compound effective for treating: diabetic gastroparesis, and impairment of hypomotility in the gastrointestinal tract such as constipation type irritable bowel syndrome; CNS related disorders such as migraine, schizophre

CONFORMATIONALLY CONSTRAINED, SYNTHETIC MACROCYCLIC COMPOUNDS

PROBLEM TO BE SOLVED: To provide a novel macrocyclic compound showing agonistic or antagonistic activity on a motilin receptor, a serotonin receptor and a prostaglandin F2A receptor. SOLUTION: This invention provides a macrocyclic compound incorporating building blocks A, B and C, represented by formula (I). The compound is useful for the treatment of motility disorders of the gastrointestinal tract, CNS-related disease and ocular hypertension. COPYRIGHT: (C)2015,JPO&INPIT