126473-96-9

Basic information

• Product Name: (1-phenyl-3-butynyloxy)methylpyrazine
• CAS NO: 126473-96-9
• Molecular Weight: 238.289
• Mol File: 126473-96-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-phenyl-3-butynyloxy)methylpyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (1-phenyl-3-butynyloxy)methylpyrazine(126473-96-9)
• EPA Substance Registry System: (1-phenyl-3-butynyloxy)methylpyrazine(126473-96-9)

Safety Data

• Hazardous Substances Data: 126473-96-9(Hazardous Substances Data)

Upstream product

• 1743-36-8 1-phenylbut-3-yn-1-ol 
• 39204-47-2 2-(chloromethyl)pyrazine 

Downstream Products

• 126474-11-1 2-(1-Phenyl-4-trimethylsilanyl-but-3-ynyloxymethyl)-pyrazine 
• 126474-18-8 6-Phenyl-4-trimethylsilanyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine 
• 126474-19-9 3-Phenyl-5-trimethylsilanyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine 
• 126474-04-2 6-Phenyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine 
• 126474-05-3 3-Phenyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine 

Relevant articles and documents

INTRAMOLECULAR INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF PYRAZINES

Thermally induced intramolecular Diels-Alder cyclisations of (alkynyloxyalkyl)pyrazines to dihydropyranopyridines have been studied in the solvent undecane.The introduction of a phenyl group in the α-position of the 3-butynyloxymethyl side chain leads to a 3-4 fold increase of the reaction rate, while the influence of a γ-phenyl group on the rate is negligible.The (3-butynyloxymethyl)pyrazine reacts about 7 times slower than the (3-propynyloxyethyl)pyrazine; the presence of a trimethylsilyl group at the terminus of the alkyne decreases in general the rate of the intramolecular cyclisation.The mechanisms are discussed.