12650-71-4 Usage
Uses
Validamycin E is an antibiotic agent as well as a potential fungicide in sheathe blight of rice.
Check Digit Verification of cas no
The CAS Registry Mumber 12650-71-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,5 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 12650-71:
(7*1)+(6*2)+(5*6)+(4*5)+(3*0)+(2*7)+(1*1)=84
84 % 10 = 4
So 12650-71-4 is a valid CAS Registry Number.
InChI:InChI=1/C26H45NO18/c28-3-7-1-9(14(33)17(36)13(7)32)27-10-2-8(4-29)23(19(38)15(10)34)44-26-22(41)20(39)24(12(6-31)43-26)45-25-21(40)18(37)16(35)11(5-30)42-25/h1,8-41H,2-6H2
12650-71-4Relevant articles and documents
Synthetic studies on antibiotic validamycins. Part 13. Total synthesis of (+)-validamycins A and E, and related compounds
Miyamoto, Yasunobu,Ogawa, Seiichiro
, p. 1013 - 1018 (2007/10/02)
(+)-Validoxylamine A (1) has been completely synthesized by deoxygenation of the validoxylamine B derivative (6) through formation of the aziridine, nucleophilic displacement with toluenethiol, reduction with Raney nickel, and deprotection. The validoxylamine A derivative (10) obtained was convertible, by glycosylation followed by deprotection, into validamycins A (2), E (3), and their analogues, which constitutes a total synthesis thereof.