126502-91-8Relevant academic research and scientific papers
A new approach to the preparation of 2-substituted tetrahydrofurans with alpha-syn selectivity
Mead,Yang
, p. 6829 - 6832 (1989)
A strategy for selectively preparing 2-substituted tetrahydrofurans bearing α-syn side chain stereochemistry, based on intramolecular 2-oxetanone ring opening, has been demonstrated. A new approach to the preparation of 3,4-disubstituted 2-oxetanones is also presented.
Intramolecular Ring Opening Reactions of 2-Oxetanones Leading to Tetrahydrofuran Ring Formation: A Lewis Acid Study
Mead, Keith T.,Yang, Hui-Li
, p. 2991 - 2992 (2007/10/02)
A study of Lewis acid mediated intramolecular ring opening reactions of 2-oxetanones has been undertaken.Using α-substituted 4-(3-benzyloxy)propyl) analogues as substrates, we have found the reaction outcome to be highly Lewis acid dependent.
