1265205-80-8Relevant academic research and scientific papers
Fast and flexible synthesis of pantothenic acid and CJ-15,801
Sewell, Alan L.,Villa, Mathew V. J.,Matheson, Mhairi,Whittingham, William G.,Marquez, Rodolfo
, p. 800 - 803 (2011)
The fast and efficient syntheses of pantothenic acid and the antiparasitic agent CJ-15,801 have been achieved starting from a common imide unit through the selective manipulation of enamide intermediates.
Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation
Spry, Christina,Sewell, Alan L.,Hering, Yuliya,Villa, Mathew V.J.,Weber, Jonas,Hobson, Stephen J.,Harnor, Suzannah J.,Gul, Sheraz,Marquez, Rodolfo,Saliba, Kevin J.
, p. 1139 - 1147 (2017/12/15)
Survival of the human malaria parasite Plasmodium falciparum is dependent on pantothenate (vitamin B5), a precursor of the fundamental enzyme cofactor coenzyme A. CJ-15,801, an enamide analogue of pantothenate isolated from the fungus Seimatosp
