599-04-2Relevant articles and documents
R(-)PANTOYLLACTONE-β-D-GLUCOPYRANOSIDE: CHARACTERIZATION OF A METABOLITE FROM RICE SEEDLINGS
Menegus, Faustino,Cattaruzza, Liliana,Ragg, Enzio,Scaglioni, Leonardo
, p. 1617 - 1622 (1995)
A new derivative of pantoic acid, R(-)pantoyllactone-β-D-glucopyranoside, has been isolated from rice seedlings and its structure determined. β-Glucosidase hydrolysed it to D-glucose and R(-)pantoyllactone.Alkaline hydrolysis converted it to the salt of 2-R(-)pantoic acid β-D-glucopyranoside.It accumulated in rice shoots but not in roots. - Keywords: Oryza sativa; Gramineae; rice seedling; pantoyllactone glucoside; pantoic acid glucoside; new metabolite; NMR signal assignment; shoot to root distribution.
Copper-Mediated Synthesis of N-Acyl Vinylogous Carbamic Acids and Derivatives: Synthesis of the Antibiotic CJ-15,801
Han, Chong,Shen, Ruichao,Su, Shun,Porco Jr., John A.
, p. 27 - 30 (2004)
(Equation presented) Copper(I)-mediated C-N bond formation has been employed to prepare both N-acyl vinylogous carbamic acids and ureas. The novel N-acyl vinylogous carbamic acid antibiotic, CJ-15,801, was synthesized using this methodology.
Synthesis of (R)-pantoyl lactone by reduction of ketopantoate with formate and Proteus species
Eck,Simon
, p. 1419 - 1422 (1994)
(R)-Pantoyl lactone (ee > 97%) is obtained by stereoselective reduction of ketopantoate with resting cells of anaerobically grown Proteus vulgaris or Proteus mirabilis. Benzyl-viologen or safranine T have been used as electron mediators.
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Velluz,Joly
, (1946)
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Optical Resolution of (R,S)-Pantolactone through Amide Formation
Fizet, Christian
, p. 404 - 409 (1986)
The optical resolution of (RS)-pantolactone (1) is carried out through formation of diastereomeric amides.These are separated by a single hot washing with CH2Cl2 or CHCl3.The used asymmetric amine, (1R)-3-endo-aminoborneol (4), is readily accessible and can be recovered almost quantitatively after resolution.
Industrial kinetic resolution ofd,l-pantolactone by an immobilized whole-cell biocatalyst
Huang, Liu-Nv,Luo, Wen-Fang,Tang, Yi-Bin,Yang, Liu,Zhang, Qiu-Hua
, p. 30373 - 30376 (2021/10/20)
Immobilized whole-cells ofPichia pastorisharboring recombinantd-lactonase were entrapped in calcium alginate gels and used as an efficient biocatalyst for catalytic kinetic resolution ofd,l-pantolactone. The immobilized whole-cell biocatalyst exhibited good catalytic stability, which was applied for stereospecific hydrolysis ofd-pantolactone for up to 56 repeated batch reactions without obvious loss in the catalytic activity and enantioselectivity.
Synthesis method of chiral 2-hydroxy-1, 4-dicarbonyl compound and pantoic acid lactone
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Paragraph 0076-0078, (2020/11/10)
The invention discloses a chiral 2-hydroxy-1, 4-dicarbonyl compound synthesized by catalyzing asymmetric Aldol reaction of fatty aldehyde and glyoxylate or fatty aldehyde and acylformaldehyde monohydrate by taking tetrapeptide TP or an enantiomer ent-TP thereof as a chiral catalyst, and application of a synthetic product. The method for synthesizing the chiral 2-hydroxy-1, 4-dicarbonyl compound through the asymmetric Aldol reaction is shown as a formula 1 and a formula 2. The asymmetric Aldol reaction of fatty aldehyde and glyoxylate or fatty aldehyde and acylformaldehyde monohydrate is catalyzed to synthesize the optically active 2-hydroxy-1, 4-dicarbonyl compound, then the optically active pantoic acid lactone can be further synthesized, and the method has advantages of mild reaction conditions, easy operation, low catalyst consumption, high yield and the like, and can synthesize the 2-hydroxy-1, 4-dicarbonyl compounds with two configurations by using tetrapeptide and the enantiomerthereof.
Preparation method of hydroxyaldehyde and method for resolving optical isomer by using electrodialysis technology
-
, (2020/12/15)
The present invention provides a process for preparing hydroxyaldehydes using an immobilized catalyst, wherein the immobilized catalyst comprises a solid support and a tertiary amine-based functionalgroup. The invention also provides a method for preparing a polyhydroxy alcohol compound and a polyhydroxy acid compound. The invention further provides a method for splitting the optical isomer fromthe raceme through electrodialysis.