126529-72-4

Basic information

• Product Name: Acetamide, N,N'-[(2-chlorophenyl)methylene]bis-
• CAS NO: 126529-72-4
• Molecular Formula: C11H13ClN2O2
• Molecular Weight: 240.689
• Mol File: 126529-72-4.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, N,N'-[(2-chlorophenyl)methylene]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N,N'-[(2-chlorophenyl)methylene]bis-(126529-72-4)
• EPA Substance Registry System: Acetamide, N,N'-[(2-chlorophenyl)methylene]bis-(126529-72-4)

Safety Data

• Hazardous Substances Data: 126529-72-4(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 126529-65-5 [Amino-(2-chloro-phenyl)-methyl]-phosphinic acid 

Relevant articles and documents

Ultrasound-promoted synthesis of symmetrical bisamides by reaction between aromatic aldehydes and amides catalysed by p-toluenesulfonic acid

Reaction between aldehydes and amides catalysed by p-toluenesulfonic acid (p-TSA), under ultrasound irradiation and ambient conditions, gives symmetrical bisamide derivatives in excellent yield and in short time.

Inhibitors of phenylalanine ammonialyase: 1-aminobenzylphosphonic acids substituted in the benzene ring

Dextrorotatory 1-amino-3′,4′-dichlorobenzylphosphonic acid was found to be a potent inhibitor of the plant enzyme phenylalanine ammonia-lyase both in vitro and in vivo from among the ring-substituted 1-aminobenzylphosphonic acids and other analogues of phenylglycine. A structure activity relationship analysis of the results obtained permits predictions on the geometry of the pocket of the enzyme and is a basis in the strategy of better inhibitor synthesis.

SYNTHESIS OF AMINOBENZYLPHOSPHONOUS ACIDS VIA DIRECT AMIDOALKYLATION OF HYPOPHOSPHOROUS ACID

Aminobenzylphosphonic acids are obtained by amidoalkylation of hypophosphorous acid with N,N'-arylidene bisamides.Key words: Aminobenzylphosphonous acid; amidoalkylation; hypophosphorous acid; N,N'-arylidene bisamides.