126559-79-3

Upstream product

• 126559-74-8 (+/-)-ethyl (E)-3,5-dihydroxy-7-(phenylthio)-hept-6-enoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 126559-76-0 (+/-)-ethyl (E)-3,5-anti-bis(t-butyldimethylsiloxy)-7-(phenylthio)-hept-6-enoate 
• 126559-73-7 (+/-)-ethyl (E)-5-hydroxy-3-oxo-7-(phenylthio)-hept-6-enoate 
• 5707-04-0 Phenylselenyl chloride 
• 126559-78-2 (+/-)-(E)-3,5-anti-bis(t-butyldimethylsiloxy)-7-(phenylthio)hept-6-enoic acid 
• 126559-76-0 (+/-)-ethyl (E)-3,5-syn-bis(t-butyldimethylsiloxy)-7-(phenylthio)-hept-6-enoate 
• 126559-78-2 (+/-)-(E)-3,5-syn-bis(t-butyldimethylsiloxy)-7-(phenylthio)hept-6-enoic acid 

Downstream Products

• 126559-72-6 (+/-)-trans-3,5-bis(t-butyldimethylsiloxy)-2-methylenecyclohexanone 
• 126559-80-6 (2RS,3SR,5SR)-3,5-bis(t-butyldimethylsiloxy)-2-(phenylthiomethyl)cyclohexanone 
• 126559-80-6 (2RS,3RS,5RS)-3,5-bis(t-butyldimethylsiloxy)-2-(phenylthiomethyl)cyclohexanone 
• 126559-80-6 (2S,3R,5S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-phenylsulfanylmethyl-cyclohexanone 
• 126559-80-6 (2R,3R,5S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-phenylsulfanylmethyl-cyclohexanone 

Relevant academic research and scientific papers

Acyl Radical Cyclizations in Synthesis. Part 3. Synthesis of (+/-)-trans-3,5-Bis(t-butyldimethylsiloxy)-2-Methylenecyclohexanone, an 'A' Ring Model for 1α,25-Dihydroxyvitamin D3

A concise synthesis of (+/-)-trans-3,5-bis(t-butyldimethylsiloxy)-2-methylenecyclohexanone has been developed.The synthesis proceeds in seven steps from ethyl acetoacetate and involves a highly efficient acyl radical cyclization to construct the six-membered ring.

An Improved Procedure for the Formation of Se-Phenyl Selenoesters

The reaction of carboxylic acids as their triethylammonium salts with benzeneselenenyl chloride in tetrahydrofuran at room temperature yields the corresponding Se-phenyl selenoesters in high yield.