12656-09-6 Usage
Uses
Different sources of media describe the Uses of 12656-09-6 differently. You can refer to the following data:
1. Siomycin is a macrocyclic antibiotic with potent and selective antibacterial activity discovered in 1969. Siomycin is a potent inhibitor of the oncogenic transcription factor, FoxM1. The reduced transcription activity is reflected in the down regulation of protein and mRNA levels of FoxM1 and effects on down stream genes, Cdc25B, survivin and CENPB. In vitro, siomycin inhibits FoxM1-induced cell growth on soft agar and selectively kill transformed but not normal cells.
2. Siomycin A is an antibiotic that inhibits FoxM1.
Check Digit Verification of cas no
The CAS Registry Mumber 12656-09-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,5 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 12656-09:
(7*1)+(6*2)+(5*6)+(4*5)+(3*6)+(2*0)+(1*9)=96
96 % 10 = 6
So 12656-09-6 is a valid CAS Registry Number.
InChI:InChI=1/C71H81N19O18S5/c1-14-37-64-83-45(22-109-64)61(103)89-52(70(13,107)34(12)93)67-85-44(23-112-67)59(101)88-49-33(11)108-68(106)39-17-36(31(9)91)35-15-16-38(51(94)50(35)80-39)79-47(25(2)3)62(104)77-29(7)56(98)74-27(5)55(97)75-30(8)57(99)90-71(69-86-46(24-113-69)60(102)87-48(32(10)92)63(105)81-37)18-40(42-20-111-66(49)82-42)78-41(19-71)65-84-43(21-110-65)58(100)76-28(6)54(96)73-26(4)53(72)95/h14-17,20-21,23-25,30-34,38,40,45,47-49,51-52,79,91-94,107H,4-7,18-19,22H2,1-3,8-13H3,(H2,72,95)(H,73,96)(H,74,98)(H,75,97)(H,76,100)(H,77,104)(H,81,105)(H,87,102)(H,88,101)(H,89,103)(H,90,99)/b37-14+
