1265612-73-4Relevant academic research and scientific papers
Modulation of PPAR subtype selectivity. Part 2: Transforming PPARα/γ dual agonist into α selective PPAR agonist through bioisosteric modification
Zaware, Pandurang,Shah, Shailesh R.,Pingali, Harikishore,Makadia, Pankaj,Thube, Baban,Pola, Suresh,Patel, Darshit,Priyadarshini, Priyanka,Suthar, Dinesh,Shah, Maanan,Jamili, Jeevankumar,Sairam, Kalapatapu V.V.M.,Giri, Suresh,Patel, Lala,Patel, Harilal,Sudani, Hareshkumar,Patel, Hiren,Jain, Mukul,Patel, Pankaj,Bahekar, Rajesh
scheme or table, p. 628 - 632 (2011/03/18)
A novel series of oxime containing benzyl-1,3-dioxane-r-2-carboxylic acid derivatives (6a-k) were designed as selective PPARα agonists, through bioisosteric modification in the lipophilic tail region of PPARα/γ dual agonist. Some of the test compounds (6a
