1265629-92-2

Upstream product

• 35512-87-9 dimethylphenylphosphine borane 
• 37860-51-8 tetraethylene glycol di(p-toluenesulfonate) 
• 1159593-68-6 (S,S)-1,2-bis[boranatophenyl(2-hydroxyethyl)phosphino]ethane 
• 169437-76-7 (S_P,S_P)-1,2-bis[(methyl)(phenyl)phosphino-P-borane]ethane 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure P-stereogenic diphosphacrowns and their palladium complexes

A practical synthetic route for enantiomerically pure P-stereogenic diphosphacrowns was developed by using a P-stereogenic bisphosphine as a chiral building block. Their molecular structures were confirmed by NMR spectroscopy and X-ray crystallography. Complexation of the diphosphacrowns with palladium was carried out, and the corresponding palladium complexes were obtained. The P-stereogenic diphosphacrowns were applicable to the chiral ligand for the asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated ketone catalyzed by palladium. This reaction proceeded smoothly to afford the corresponding 1,4-addition products in high yield with good enantioselectivities.