126565-31-9Relevant academic research and scientific papers
N-HYDROXYUREA DERIVATIVES
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, (2008/06/13)
An N-hydroxyurea derivative or a pharmacologically acceptable salt thereof having the formula (I): wherein, A represents CH, CH-CH2, CH-O, or C=CH, X represents O or S, B represents a C1to C8alkylene, C2to C6alkenylene, m-phenylene, or p-phenylene, R represents a hydrogen atom, halogen atom, C1to C4alkyl which may be substituted with a halogen atom, C1to C4alkoxy which may be substituted with a halogen atom, or nitro, R1represents a hydrogen atom, C1to C4lower alkyl, or phenyl, and R2represents a hydrogen atom, C1to C4alkyl, cycloalkyl, phenyl which may be substituted with a substituent, or methanesulfonyl.
Thromboxane Synthetase Inhibitors (TXSI). Design, Synthesis, and Evaluation of a Novel Series of ω-Pyridylalkenoic Acids
Kato, Kaneyoshi,Ohkawa, Shigenori,Terao, Shinji,Terashita, Zen-ichi,Nishikawa, Kohei
, p. 287 - 294 (2007/10/02)
A novel series of ω-pyridylalkenoic acids has been prepared by applying the Wittig reaction.Modifications were made in the ω-aryl moiety, the alkylene chain length, the α-methylene group adjacent to the carbonyl group, and the carboxyl group in the molecu
