126587-54-0

Basic information

• Product Name: [(1R,2S)-1-(Imidazole-1-carbonyl)-2-methyl-butyl]-carbamic acid benzyl ester
• Synonyms: [(1R,2S)-1-(Imidazole-1-carbonyl)-2-methyl-butyl]-carbamic acid benzyl ester
• CAS NO: 126587-54-0
• Molecular Weight: 315.372
• Mol File: 126587-54-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(1R,2S)-1-(Imidazole-1-carbonyl)-2-methyl-butyl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(1R,2S)-1-(Imidazole-1-carbonyl)-2-methyl-butyl]-carbamic acid benzyl ester(126587-54-0)
• EPA Substance Registry System: [(1R,2S)-1-(Imidazole-1-carbonyl)-2-methyl-butyl]-carbamic acid benzyl ester(126587-54-0)

Safety Data

• Hazardous Substances Data: 126587-54-0(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 3160-59-6 N-benzyloxycarbonylamino-D-alloisoleucine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 1509-35-9 D-alloisoleucine 
• 62210-73-5 N-<<(benzyloxy)carbonyl>oxy>-5-norbornene-2,3-dicarboximide 

Downstream Products

• 129919-83-1 (3S,4R,5S)-4-<<(benzyloxy)carbonyl>amino>-3-<(triisopropylsilyl)oxy>-5-methyl-heptanoic acid, (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl ester 
• 130008-94-5 (3R,4R,5S)-4-<<(benzyloxy)carbonyl>amino>-3-<(triisopropylsilyl)oxy>-5-methyl-heptanoic acid, (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl ester 
• 126587-62-0 N-<1--L-leucyl>-L-prolyl>-3-(p-methoxyphenyl)-N-methyl-L-alanine, ester with (3S,4R,5S)-3-<(triisopropylsilyl)oxy>-4-<(2S,3R)-2-<(tert-butoxycarbonyl)amino>-3-hydroxybutyramido>-5-methylheptanoic acid, (1S,2S,3R)-4- 
• 126587-64-2 N-<1--L-leucyl>-L-prolyl>-3-(p-methoxyphenyl)-N-methyl-L-alanine, ester with (3S,4R,5S)-3-<(triisopropylsilyl)oxy>-4-<(2S,3R)-2-<(tert-butoxycarbonyl)amino>-3-hydroxybutyramido>-5-methylheptanoic acid, (1S,2S,3S)-1-isopropyl-2- 
• 1053630-19-5 C₆₆H₁₀₇N₅O₁₆Si 
• 126587-63-1 N-<1--L-leucyl>-L-prolyl>-3-(p-methoxyphenyl)-N-methyl-L-alanine, ester with (3S,4R,5S)-3-<(triisopropylsilyl)oxy>-4-<(2S,3R)-2-<(tert-butoxycarbonyl)amino>-3-hydroxybutyramido>-5-methylheptanoic acid, (1S,2S,3R)-4-hydroxy-1-isop 
• 148339-15-5 C₅₈H₁₀₁N₅O₁₅Si 
• 126587-70-0 (4R,5S)-4-<<(benzyloxy)carbonyl>amino>-3-hydroxy-5-methyl-heptanoic acid, (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl ester 
• 118812-53-6 (4R,5S)-4-Benzyloxycarbonylamino-5-methyl-3-oxo-heptanoic acid ethyl ester 
• 126587-55-1 (4R,5S)-4-<<(benzyloxy)carbonyl>amino>-5-methyl-3-oxoheptanoic acid, (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl ester 

Relevant articles and documents

Enantioselective and diastereoselective formation of syn-3-hydroxy-4-amino acids (syn-statines) via tetramic acids

Enantiomerically pure pyrrolidine-2,4-diones (tetramic acids) which can be diastereoselectively hydrogenated to syn-statines (4-amino-3-hydroxy-6-methylheptanoic acids) have been prepared by catalytic hydrogenation of 4-(benzyloxycarbonylamino)-3-oxocarboxylic acid esters.

SYNTHETIC STUDIES OF DIDEMNINS. IV. SYNTHESIS OF THE MACROCYCLE

A stereocontrolled route to the 23-membered macrocycle found in the didemnins is described.