126589-88-6

Basic information

• Product Name: 1,4-Butanediol, 2-[(acetyloxy)methyl]-, 1-acetate
• CAS NO: 126589-88-6
• Molecular Formula: C9H16O5
• Molecular Weight: 204.223
• Mol File: 126589-88-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-Butanediol, 2-[(acetyloxy)methyl]-, 1-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Butanediol, 2-[(acetyloxy)methyl]-, 1-acetate(126589-88-6)
• EPA Substance Registry System: 1,4-Butanediol, 2-[(acetyloxy)methyl]-, 1-acetate(126589-88-6)

Safety Data

• Hazardous Substances Data: 126589-88-6(Hazardous Substances Data)

Usage

Synonyms

Acetoacetic acid monoester of 1,4-butanediol

Usage

Solvent
Production of plastics and polymers
Precursor for the synthesis of various chemicals

Industrial applications

Component in the production of coatings, adhesives, and sealants
Manufacture of pharmaceuticals
Production of personal care products

Hazardous nature

Careful handling required due to potential hazards if not used properly.

Upstream product

• 17739-45-6 2-(2-bromoethoxy)tetrahydropyran 

Downstream Products

• 126589-82-0 2-Acetoxymethyl-4-bromobut-1-yl acetate 
• 97845-60-8 9-<4-acetoxy-3-(acetoxymethyl)butyl>-2-amino-6-chloro-9H-purine 
• 128139-38-8 Acetic acid 2-acetoxymethyl-4-methanesulfonyloxy-butyl ester 
• 128139-27-5 9-(4-acetoxy-3-acetoxymethylbutyl)-2-amino-6-iodopurine 
• 131266-20-1 9-(4-acetoxy-3-acetoxymethylbutyl)-2-amino-6-bromopurine 
• 127047-77-2 4-acetoxy-3-(acetoxymethyl)-1-iodobutane 
• 225111-66-0 9-<4-acetoxy-3-(acetoxymethyl)butyl>-2-amino-6-<(4-chlorophenyl)sulfanyl>-9H-purine 
• 39809-25-1 Penciclovir 
• 97845-61-9 7-(4-acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine 
• 104227-87-4 9-(4-acetoxy-3-acetoxymethylbutyl)-2-aminopurine 

Relevant articles and documents

Preparation method for 2-amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutyl)purine

The invention relates to a preparation method for 2-amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutyl)purine. The method comprises the following steps: performing a reaction on 1,3-dichloro-2-propanoland an acetate to obtain 1,3-diacetoxy-2-propanol, performing a bromination reaction to obtain 1,3-diacetoxy-2-bromopropane, performing a reaction on the 1,3-diacetoxy-2-bromopropane and zinc powder to obtain 1,3-diacetoxy-2-zinc bromide propane, performing a coupling reaction on the 1,3-diacetoxy-2-zinc bromide propane and 2-bromoethanol protected by hydroxyl, and performing a de-protection reaction to obtain 1,3-diacetoxy-2-(2-hydroxyethyl)propane, and performing a Mitsunobu reaction on the 1,3-diacetoxy-2-(2-hydroxyethyl)propane and 2-amino-6-chloropurine to obtain the 2-amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutyl)purine. According to the method provided by the invention, the 2-amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutyl)purine prepared by the method has purity of 99.5% or more detected by HPLC, and can be used to prepare famciclovir and penciclovir.