1266134-11-5

Basic information

• Product Name: 1,1-bis(4-fluorophenyl)-2-oxopropyl benzoate
• Synonyms: 1,1-bis(4-fluorophenyl)-2-oxopropyl benzoate
• CAS NO: 1266134-11-5
• Molecular Weight: 366.364
• Mol File: 1266134-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-bis(4-fluorophenyl)-2-oxopropyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-bis(4-fluorophenyl)-2-oxopropyl benzoate(1266134-11-5)
• EPA Substance Registry System: 1,1-bis(4-fluorophenyl)-2-oxopropyl benzoate(1266134-11-5)

Safety Data

• Hazardous Substances Data: 1266134-11-5(Hazardous Substances Data)

Upstream product

• 357-77-7 1,1-bis(4-fluorophenyl)prop-2-yn-1-ol 
• 65-85-0 benzoic acid 

Relevant articles and documents

Ruthenium(IV)-catalyzed markovnikov addition of carboxylic acids to terminal alkynes in aqueous medium

The dimeric bis(allyl)ruthenium(IV) complex [{RuCl(μ-Cl)( η3:η3-C10H16)}2] (C10H16 = 2,7-dimethylocta-2,6-diene-1,8-diyl) (5) and several mononuclear species trans-[RuCl2(η3: η3-C10H16)(L)] (L = two-electron-donor ligand) (6) derived from 5 have been checked as catalysts for the addition of carboxylic acids onto terminal alkynes using water as a green reaction medium. The best results in terms of activity and regioselectivity were obtained with the mononuclear derivative trans-[RuCl2(η3: η3-C10H16)(PPh3)] (6a), which was able to promote the selective Markovnikov addition of both aromatic and aliphatic carboxylic acids to a large variety of terminal alkynes, enynes, and diynes as well as propargylic alcohols. In this way, a wide number of enol esters and β-oxo esters could be synthesized in moderate to good yields under mild conditions (60 °C) in an aqueous medium.