126655-21-8

Basic information

• Product Name: (7aβ)-1β,2α,7β-Trihydroxyhexahydro-1H-pyrrolizine-3β-methanol
• Synonyms: (+)-7-Epiaustraline;(1R,7aR)-Hexahydro-3β-(hydroxymethyl)-1H-pyrrolizine-1β,2α,7β-triol;(1R,7aβ)-Hexahydro-3β-(hydroxymethyl)-1H-pyrrolizine-1β,2α,7β-triol;(7aβ)-1β,2α,7β-Trihydroxyhexahydro-1H-pyrrolizine-3β-methanol;7,7a-Diepialexine;7-epi-Australine;(1R,2R,3R,7R,7aR)-Hexahydro-3-(hydroxymethyl)-1H-pyrrolizine-1,2,7-triol
• CAS NO: 126655-21-8
• Molecular Formula: C8H15NO4
• Molecular Weight: 189.21
• Mol File: 126655-21-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (7aβ)-1β,2α,7β-Trihydroxyhexahydro-1H-pyrrolizine-3β-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (7aβ)-1β,2α,7β-Trihydroxyhexahydro-1H-pyrrolizine-3β-methanol(126655-21-8)
• EPA Substance Registry System: (7aβ)-1β,2α,7β-Trihydroxyhexahydro-1H-pyrrolizine-3β-methanol(126655-21-8)

Safety Data

• Hazardous Substances Data: 126655-21-8(Hazardous Substances Data)

Upstream product

• 620160-84-1 (1R,2R,3R,7R,7aR)-1,2,7-triacetoxy-3-(acetoxymethyl)hexahydro-1H-pyrrolizine 
• 537030-19-6 (2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-3,4-dihydro-2H-pyrrole 1-oxide 
• 302353-82-8 Toluene-4-sulfonic acid 2-[3-((1S,2R,3R)-3-azido-1,2,4-tris-benzyloxy-butyl)-oxiranyl]-ethyl ester 
• 212612-94-7 (1R,2R,3R,7aR)-7-benzyloxy-3-{(dimethyl[1,1,2-trimethylpropyl]siloxy)methyl}-1-(dimethylphenylsilyl)hexahydro-1H-pyrrolizin-2-ol 
• 618384-74-0 (-)-(3aS,3bR,4R,8R,8aR)-4-[2-(4-methoxyphenyl)methoxy]ethyl-8-phenylmethoxylmethyltetrahydro-3aH-[1,3,2]-dioxothiolo[4',5':3,4]pyrrolo[1,2-c][1,3]oxazol-6-one 2,2-dioxide 
• 618384-55-7 (-)-(1R,5R,6R,7S,7aR)-1-[2-(4-methoxyphenyl)methoxy]ethyl-5-(phenylmethoxy)methyl-5,6,7,7a-tetrahydro-6,7-dihydroxy-1H,3H-pyrrolo[1,2-c]oxazol-3-one 
• 618384-87-5 (3aS,3bR,4R,7R,7aR)-7-Benzyloxymethyl-4-[2-(4-methoxy-benzyloxy)-ethyl]-2-oxo-tetrahydro-1,3,5-trioxa-2λ⁴-thia-6a-aza-cyclopenta[a]pentalen-6-one 
• 618384-50-2 (+)-4S-ethenyl-5R-[2-(4-methoxyphenyl)methoxy]ethyl-3-(1S-phenylmethoxymethyl-2-propenyl)-1,3-oxazolidin-2-one 
• 618384-48-8 (3R,4S)-4-((S)-1-Benzyloxymethyl-allylamino)-1-(4-methoxy-benzyloxy)-hex-5-en-3-ol 
• 618384-84-2 (+)-(1R,2R,3R,7R,7aR)-1,2,7-triacetoxy-3-(phenylmethoxy)methylhexahydro-1H-pyrrolizine 
• 618384-80-8 (+)-(2R,3R,4R,5R)-5-[(1R)-1,3-dihydroxypropyl]-2-(phenylmethoxy)methylpyrrolizine-3,4-diol 
• 268202-19-3 Acetic acid (1R,2R,3R,7R,7aR)-2,7-diacetoxy-3-hydroxymethyl-hexahydro-pyrrolizin-1-yl ester 
• 618384-82-0 (1R,2R,3R,7R,7aR)-3-Benzyloxymethyl-hexahydro-pyrrolizine-1,2,7-triol 
• 459870-75-8 6-(4-methoxyphenyl)methoxy-3,4-epoxy-1-hexene 

Relevant articles and documents

Stereocomplementary routes to hydroxylated nitrogen heterocycles: Total syntheses of casuarine, Australine, and 7-epi-Australine

Addition of lithiated 1-benzyloxyallene to a D-arabinose-derived cyclic nitrone occurred with perfect diastereoselectivity furnishing a bicyclic 1,2-oxazine derivative, which is an excellent precursor for pyrrolizidine alkaloids hydroxylated at C-7 with o

Asymmetric synthesis of ( - )-7-epiaustraline and (+)-1,7-diepiaustraline

A diastereoselective and modular approach to the synthesis of the 3-hydroxymethyl-2,3,5,6,7,7a-hexahydro-1H-pyrrolizine-1,2,7-triol structure, characteristic of several natural pyrrolizidine natural products, has been developed. This approach culminated i

Synthesis of (1R,2R,3R,7R,7aR)-hexahydro. 3-(hydroxymethyl)- 1H- pyrrolizine-1,2,7-triol: 7-Epiaustraline [6]

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