1266610-47-2Relevant academic research and scientific papers
Indole synthesis by conjugate addition of anilines to activated acetylenes and an unusual ligand-free copper(II)-mediated intramolecular cross-coupling
Gao, Detian,Back, Thomas G.
, p. 14828 - 14840 (2013/01/15)
A versatile new synthesis of indoles was achieved by the conjugate addition of N-formyl-2-haloanilines to acetylenic sulfones, ketones, and esters followed by a copper-catalyzed intramolecular C-arylation. The conjugate addition step was conducted under e
Synthesis of indoles by conjugate addition and ligand-free copper-catalyzed intramolecular arylation of activated acetylenes with o-haloanilines
Gao, Detian,Parvez, Masood,Back, Thomas G.
supporting information; experimental part, p. 14281 - 14284 (2011/03/19)
Air and water welcome-ligands need not apply! A simple and efficient new synthesis of variously functionalized and substituted indoles was achieved by the addition and copper-catalyzed coupling of N-formyl-o-haloanilines with acetylenic sulfones, esters a
