1266728-09-9

Basic information

• Product Name: methyl 3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}benzoate
• Synonyms: methyl 3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}benzoate
• CAS NO: 1266728-09-9
• Molecular Weight: 443.497
• Mol File: 1266728-09-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}benzoate(1266728-09-9)
• EPA Substance Registry System: methyl 3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}benzoate(1266728-09-9)

Safety Data

• Hazardous Substances Data: 1266728-09-9(Hazardous Substances Data)

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 1229244-95-4 methyl 3-bromo-5-(3-hydroxypropyl)-4-methylbenzoate 
• 74896-66-5 Methyl 3,5-Dibromo-4-methylbenzoate 
• 1229245-00-4 methyl 3-bromo-5-[(1E)-3-methoxy-1-propen-1-yl]-4-methylbenzoate 
• 1229244-99-8 methyl 3-bromo-5-(3-methoxypropyl)-4-methylbenzoate 

Downstream Products

• 1266728-08-8 {3-[3-bromo-5-(bromomethyl)-2-methylphenyl]propoxy}(triisopropyl)silane 
• 1266728-10-2 (3-bromo-4-methyl-5-{3-[(triisopropylsilyl)oxy]propyl}phenyl)methanol 

Relevant articles and documents

RENIN INHIBITORS

Renin inhibitors, which are spirocyclic piperidine amides, of structural formula (I) and pharmaceutical compositions thereof useful in the treatment of cardiovascular diseases and renal insufficiency, wherein n, for each instance in which it occurs, is independently 0, 1, or 2; R1 is hydrogen, C1-6 -alkyl or C3-6 -cycloalkyl, wherein said C1-6 -alkyl or C3-6 -cycloalkyl group can be independently substituted with 1-3 halogens; A is (i) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic monocyclic ring or (ii) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring which is fused to another five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring, V is a bond or -(C=O)-, -CH(OH)-, -CH2- or =CH-; U is a bond or -CH2-, or for the case when V is =CH-, U is -CH=; X is =CH-, =CF-, =C(OR3)-, or -C=O-; and Y is =CH-, =CF-, =N-, or for the case when X is -C=O-, Y is -N(R3)-.