126680-18-0Relevant academic research and scientific papers
NOVEL SYNTHESIS OF 1,7-DIHYDROHEPT-4-YNE DERIVATIVES : APPLICATION TO THE TOTAL SYNTHESIS OF (+/-) PATULOLIDE A
Yadav, J. S.,Krishna, P. Radha,Gurjar, M. K.
, p. 6263 - 6270 (2007/10/02)
Methodology for the synthesis of 1,7-dihydrohept-4-yne derivatives by the in situ alkylation of tetrahydrofurfuryl chloride (1) by the epoxides (3a-e) is developed and the importance of such an endeavour is exemplified in the synthesis of (+/-) Patulolide
