126694-56-2Relevant academic research and scientific papers
The First Internally Functionalized Chiral Metacyclophanes
Voegtle, Fritz,Ostrowicki, Andreas,Knops, Peter,Fischer, Peter,Reuter, Hans,Jansen, Martin
, p. 1757 - 1759 (1989)
The new medium membered heterocycles (2c-i), additionally strained due to internal substituents, could be obtained after optimization of a simple one-step cyclisation reaction; the barrier of the restricted rotations of the phenyl ring in (2h) and of the
Intra- and Extraannularly Functionalized Chiral Metacyclophanes: Synthesis, Circular Dichroism, and Structure - Chiroptic Relationships
Voegtle, Fritz,Knops, Peter,Ostrowicki, Andreas
, p. 1859 - 1868 (2007/10/02)
A simple one-step cyclization reaction for the synthesis of the title compounds 1 - 5 is presented; separation (enrichment) of enantiomers is achieved by HPLC mainly on (+)-PTrMA.The kinetics of interconversion (racemization) of the new diheterametac
