126727-02-4

Basic information

• Product Name: Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Synonyms: Fmoc-DL-valine;Fmoc-VAL-OH;Fmov-Val;N-Fmoc-valine;9-fluorenylmethoxycarbonylvaline;Fmoc-valine
• CAS NO: 126727-02-4
• Molecular Formula: C20H21NO4
• Molecular Weight: 339.391
• Mol File: 126727-02-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 551.8±33.0 °C(Predicted)
• Density: 1.229±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-(126727-02-4)
• EPA Substance Registry System: Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-(126727-02-4)

Safety Data

• Hazardous Substances Data: 126727-02-4(Hazardous Substances Data)

Usage

General Description

Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- is a chemical compound that is derived from the amino acid valine. It is commonly used as a building block in the synthesis of various peptides and proteins. Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- is often utilized in biochemical research and drug development due to its ability to modify and stabilize the structure of peptides and proteins. It is also known to possess potential therapeutic properties and may be studied further for its pharmacological applications. Additionally, valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- is considered a valuable tool in the field of biochemistry, particularly in the study of protein structures and functions.

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 516-06-3 D,L-valine 

Downstream Products

• 92466-88-1 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methyl-butyric acid 2,4,5-trichloro-phenyl ester 
• 68858-20-8 Fmoc-Val-OH 
• 84624-17-9 N-(9-fluorenylmethoxycarbonyl)-D-valine 
• 4425-82-5 9-methylene-fluorene 

Relevant articles and documents

Determination of Chemical and Enantiomeric Purity of α-Amino Acids and their Methyl Esters as N-Fluorenylmethoxycarbonyl Derivatives Using Amylose-derived Chiral Stationary Phases

Liquid chromatographic enantiomer separation and simultaneous determination of chemical and enantiomeric purity of α-amino acids and their methyl esters as N-fluorenylmethoxycarbonyl (FMOC) derivatives was performed on three covalently bonded type chiral stationary phases (CSPs) derived from amylose derivatives. The enantiomer separation of α-amino acid esters as N-FMOC derivatives was better than that of the corresponding acids, especially for CSP 1 and 2. Chemical impurities as the corresponding racemic acids present in several commercially available racemic amino acid methyl esters were observed to be 0.49–17.50%. Enantiomeric impurities of several commercially available L-amino acid methyl esters were found to be 0.03–0.58%, whereas chemical impurities as the corresponding racemic acids present in the same analytes were found to be 0.13–13.62%. This developed analytical method will be useful for the determination of chemical and enantiomeric purity of α-amino acids and/or esters as N-FMOC derivatives using amylose-derived CSPs.