1267386-09-3Relevant academic research and scientific papers
Designed spiro-bicyclic analogues targeting the ribosomal decoding center
Cottin, Thomas,Pyrkotis, Constantina,Stathakis, Christos I.,Mavridis, Ioannis,Katsoulis, Ioannis A.,Anastasopoulou, Panoula,Kythreoti, Georgia,Zografos, Alexandros L.,Nahmias, Victoria R.,Papakyriakou, Athanasios,Vourloumis, Dionisios
experimental part, p. 71 - 87 (2011/12/16)
The bacterial ribosome represents the confirmed biological target for many known antibiotics that interfere with bacterial protein synthesis. Aminoglycosides represent a lead paradigm in RNA molecular recognition and constitute ideal starting points for t
