1267436-53-2Relevant academic research and scientific papers
Synthesis of new spiro compounds containing a carbamate group
Velikorodov,Poddubnyi,Kuanchalieva,Krivosheev
, p. 1826 - 1829 (2011/04/15)
1,3-Dipolar cycloaddition to methyl 4-[2-(2-oxo-2,3-dihydro-1H-indol-3- ylidene)-1-oxoethyl]-phenylcarbamate of diazomethane in chloroform-diethyl ether and of 3,4-dimethoxybenzonitrile oxide generated from the corresponding aldehyde oxime by the action of N-chlorobenzenesulfonamide sodium salt (Chloramine B) in boiling ethanol gave, respectively, methyl 4-(2-oxo-1′,5′-dihydro-1H-spiro[indole-3,4′-pyrazol] -3′-ylcarbonyl)phenylcarbamate and methyl 4-[3′-(3,4- dimethoxyphenyl)-2-oxo-1H,4′H-spiro[indole-3,5′-isoxazol] -4′-ylcarbonyl]phenylcarbamate. The condensation of methyl 4-[2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)-1-oxoethyl]phenylcarbamate with hydrazine hydrate in ethanol afforded methyl 4-(2-oxo-1,2,2′,4′- tetrahydrospiro[indole-3,3′-pyrazol]-5′-yl)phenylcarbamate. Pleiades Publishing, Ltd., 2010.
