126748-44-5Relevant articles and documents
Chiral Carboxylic Acid Enabled Achiral Rhodium(III)-Catalyzed Enantioselective C?H Functionalization
Lin, Luqing,Fukagawa, Seiya,Sekine, Daichi,Tomita, Eiki,Yoshino, Tatsuhiko,Matsunaga, Shigeki
supporting information, p. 12048 - 12052 (2018/09/11)
Reported is an achiral CpxRhIII/chiral carboxylic acid catalyzed asymmetric C?H alkylation of diarylmethanamines with a diazomalonate, followed by cyclization and decarboxylation to afford 1,4-dihydroisoquinolin-3(2H)-one. Secondary
A new simple method for the preparation of aryl formates from phenols
Hashmi, Imran Ali,Kantlehner, Willi,Ivanov, Ivo C.
experimental part, p. 478 - 480 (2009/01/31)
Aryl formates are prepared in a two step one-pot procedure from phenols. Firstly the formylating reagent triformamide (1b) is generated from sodium diformamide (2) and methane-sulfonyl chloride in situ, which reacts with phenols 4a-f to give aryl formates 5a-f in good yields. Triformamide, prepared in situ, transforms anisole in the presence of aluminum chloride to the N-(diarylmethyl)formamide 7.
Orthoamides. LIII. A New Synthesis for Aromatic Aldehydes of Wide Scope
Kantlehner, Willi,Vettel, Markus,Gissel, Alexander,Haug, Erwin,Ziegler, Georg,Ciesielski, Michael,Scherr, Oliver,Haas, Richard
, p. 297 - 310 (2007/10/03)
Diformamide (1) reacts with activated aromatic compounds like toluene, anisole, m-xylene, 1,2-dimethoxybenzene in the presence of AlCl3 to give N-(diarylmethyl)-formamides 2a-d, the corresponding aromatic aldehydes 3-6 are formed as by-products in low yields. From N,N-dimethylaniline and 1/AlCl3 the triphenylmethane derivative 7 can be obtained. The reaction of anisole with N-methyl-diformamide (9) affords the formamide 10. The mixture of formamide, P4O10 and AlCl3 reveals to be a reagent which is capable to formylate toluene and anisole, resp. Triformamide (14)/AlCl3 is an effective formylating system which allows the preparation of aromatic aldehydes (e.g. 3,4,17-32) from the corresponding aromatic hydrocarbons. Aluminiumchloride can be replaced by borontrichloride. The yields of the formylation reactions depend strongly from the reaction conditions (molar ratio: aromatic hydrocarbon/ AlCl3/14; solvent, reaction temperature). The scope of the reaction covers nearly complete those of the Gattermann-Koch-, Gattermann- and Vilsmeier-Haack-reaction.
One-Step Hydroxy Substitution of 4,4′-Dimethoxybenzhydrol with Amides, Lactams, Carbamates, Ureas and Anilines
Henneuse, Catherine,Boxus, Thierry,Tesolin, Lorenzo,Pantano, Guiseppe,Marchand-Brynaert, Jacqueline
, p. 495 - 501 (2007/10/03)
A series of amides, lactams, carbamates, ureas and anilines, equipped with various functionalities, were readily N-alkylated with the 4,4′-dimethoxybenzhydryl residue by reaction with 4,4′-dimethoxybenzhydrol [bis(4-methoxyphenyl)methanol] in acetic acid,
Towards the rehabilitation of the Leuckart reductive amination reaction using microwave technology
Loupy, Andre,Monteux, Daphne,Petit, Alain,Aizpurua, Jesus Ma.,Dominguez, Esther,Palomo, Claudio
, p. 8177 - 8180 (2007/10/03)
Leuckart reductive amination of carbonyl compounds was dramatically enhanced with respect to conventional heating by a specific microwave effect when the reaction was performed, under solvent-free conditions, in a monomode microwave reactor. Excellent iso
