1267585-85-2Relevant academic research and scientific papers
Peptide deformylase inhibitors with non-peptide scaffold: Synthesis and structure-activity relationships
Lee, Seung Kyu,Choi, Kwang Hyun,Lee, Sang Jae,Lee, Jong Sun,Park, Ji Yun,Kim, B. Moon,Lee, Bong Jin
supporting information; experimental part, p. 133 - 136 (2011/02/25)
Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies
