1267635-99-3Relevant academic research and scientific papers
Ligand-controlled iron-catalyzed cross coupling of benzylic chlorides with aryl Grignard reagents
Kawamura, Shintaro,Nakamura, Masaharu
supporting information, p. 183 - 185 (2013/03/28)
The selective cross coupling of benzylic chlorides with aryl Grignard reagents has been achieved by using catalytic amounts of FeCl2 and electronically tuned ortho-phenylenebisphosphine ligands. Although electron-deficient ligands promoted the reductive homocoupling of benzylic halides, electron-rich ligands effectively promoted the desired cross-coupling reaction to afford the corresponding diarylmethanes in good to excellent yields.
Diastereoselective carbometalation of Oxa- and azabicyclic alkenes under iron catalysis
Ito, Shingo,Itoh, Takuma,Nakamura, Masaharu
supporting information; experimental part, p. 454 - 457 (2011/03/16)
Highly diastereoselective carbometalation of oxa- and azabicyclic alkenes with arylzinc reagents has been achieved by using FeCl3 and novel ortho-phenylene diphosphine ligands (see scheme; E=electrophile). The carbozincation products are stable towards β-heteroatom elimination and can be trapped with various electrophiles.
