126781-38-2Relevant articles and documents
Selenium analogues of (S)-clopidogrel: Preparation method and properties
Vasiljeva, Jelena,Domracheva, Ilona,Arsenyan, Pavel
, p. 196 - 198 (2016)
A simple approach to prepare selenium containing analogues of (S)-clopidogrel using selenophene ring construction was developed. Evaluation of the antiproliferative activity profile confirmed that the introduction of a selenium atom into the molecule of c
Nickel-Catalyzed Decarboxylative Alkenylation of Anhydrides with Vinyl Triflates or Halides
Chen, Hui,Sun, Shuhao,Liao, Xuebin
supporting information, p. 3625 - 3630 (2019/05/24)
Decarboxylative cross-coupling of aliphatic acid anhydrides with vinyl triflates or halides was accomplished via nickel catalysis. This methodology works well with a broad array of substrates and features abundant functional group tolerance. Notably, our approach addresses the issue of safe and environmental installation of methyl or ethyl group into molecular scaffolds. The method possesses high chemoselectivity toward alkyl groups when aliphatic/aromatic mixed anhydrides are involved. Furthermore, diverse ketones could be modified with our strategy.
VMAT INHIBITORY COMPOUNDS
-
Paragraph 0433-0435, (2016/04/01)
Disclosed herein are compounds that bind to the vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions comprising those compounds, and methods of treatment using said compounds and pharmaceutical compositions.