126791-01-3

Upstream product

• 126790-88-3 N-(pyridin-4-ylmethyl)-4-methylbenzenesulfonamide 
• 126790-93-0 4-(2,5-Dichlorophenylsulfonylaminomethyl)pyridine 1-Oxide 
• 98-59-9 p-toluenesulfonyl chloride 
• 126790-87-2 2,5-Dichloro-N-(4-pyridylmethyl)benzenesulfonamide 
• 5402-73-3 2,5-dichlorobenzenesulphonyl chloride 
• 3731-53-1 4-(aminomethyl)pyridine 

Relevant academic research and scientific papers

Synthesis of N,N'-Bis(phenylsulfonyl)-1,2-bis(4-pyridyl)ethylenediamines

Reaction of (4-pyridylmethyl)amine (3) with benzenesulfonyl chlorides 2a-i affords the corresponding N-(4-pyridylmethyl)benzenesulfonamides 4a-i which are converted into the N-oxides 5 by treatment with hydrogen peroxide and acetic acid.Treatment of compounds 4 with their N-oxides 5 in acetic anhydride results in dimerization to give the corresponding N,N'-bis(phenylsulfonyl)-1,2-bis(4-pyridyl)ethylenediamines 6a-d,f.The mixed ethylenediamines 6e,g are similarly synthesized from differently substituted sulfonamides and N-oxides.