126806-48-2

Upstream product

• 126806-60-8 2-(4-Methoxyphenyl)-3-(pyridin-4-yl)-7-oxo-5,6-dihydro-7H-pyrrolo[1,2-a]imidazole 
• 126806-57-3 7-[Hydroxy-(4-nitro-phenyl)-methyl]-1-(2-methoxy-ethoxymethyl)-2-(4-methoxy-phenyl)-3-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium; chloride 
• 126806-55-1 1-(2-Methoxy-ethoxymethyl)-2-(4-methoxy-phenyl)-3-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium; chloride 
• 126806-56-2 [2-(4-Methoxy-phenyl)-3-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-7-yl]-(4-nitro-phenyl)-methanol 
• 111908-95-3 2-(4-methoxyphenyl)-3-(4-pyridyl)-6,7-dihydro-[5H]-pyrrolo [1,2-a]imidazole 

Relevant academic research and scientific papers

Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages

A method of inhibiting the production of interleukin-1 by monocytes and/or macrophages in a human in need thereof which comprises administering to such a human an effective, interleukin-1 production inhibiting amount of a diaryl-substituted imidazole fuse

C-7 FUNCTIONALIZATION OF 6,7-DIHYDROPYRROLOIMIDAZOLES: ACTIVATION VIA QUATERNIZATION WITH MEMCl.

Several 6,7-dihydropyrroloimidazoles were activated toward functionalization at C-7 by conversion to quaternary imidazolium salts.The MEMCl derived quaternary salts upon treatment with base reacted with both aldehydes and alkyl halides.The MEM group was removed under mild conditions by heating the functionalized adducts in a variety of solvents.